Day 2 at Le Mans started with a fully wet track and the surface saw a little more rainfall as the premier class got going for their third practice session. There were a few riders who loved the conditions and went quick straight away but once rain stopped and the track started changing, it was a familiar face making the headlines once more, with Marc Marquez back in charge by six tenths of a second and the only time in the 1:40s. His closest rival was surprisingly Lorenzo Savadori, the rookie showing glimpses of speed in the wet on Friday as well and turning it into second position in FP3, helped by chasing around a rapid Miguel Oliveira. The KTM man had a stint at the top as well, before dropping back to fourth, behind Pecco Bagnaia, the Italian fast in FP3 but still having to contend with Q1, as conditions on Saturday morning did not allow any changes in the combined standings.
Pol Espargaro completed the top five for Honda and was the last rider to post a time within a second of his teammate, ahead of Johann Zarco. The Suzukis spent most of the session towards the front as well, Joan Mir leading Alex Rins in 7th and 8th spots, but both due to meet up in Q1. Iker Lecuona added another KTM to the sharp end despite an early tumble, while rookie Luca Marini rounded out the top 10. The LCR duo of Alex Marquez and Takaaki Nakagami missed out by two tenths of a second, ahead of Aleix Espargaro, who had to handle some early technical issues, while the early leader of the session and wet weather enthusiast Danilo Petrucci eventually dropped to 14th.
Yamaha did not seem to enjoy the welcome they got on Saturday morning, Maverick Viñales being their top representative in 16th position, ahead of Franco Morbidelli and with Fabio Quartararo in 19th. Jack Miller topped the session early on but did not rejoin after a crash at turn 6 and got demoted to 20th spot, ahead of Valentino Rossi.