After missing the last four races due to injury, Andrea Iannone is to make a return to the Factory Ducati team. Iannone had fractured his T3 vertebra in a practice crash at Misano, and was ruled out of the race. Since then, Iannone has been forced to miss the MotoGP rounds at Aragon, Motegi and Phillip Island.
At Aragon, Iannone was replaced by official test rider Michele Pirro, but Pirro was unable to race at the overseas circuits as he had important test work to do for Ducati, getting the Desmosedici GP17 ready for Jorge Lorenzo, who will get his first chance to test the bike at Valencia, after the last race of the season. After Casey Stoner turned down the opportunity, Hector Barbera was promoted from the Avintia squad to take over Iannone's bike, while Australian Mike Jones stepped in to replace Barbera at Avintia.